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Basic Principle of SPE

Solid-phase extraction (SPE) is a sample preparation technique that concentrate and purify analytes from solution by sorption onto the disposable solid phase cartridge, followed by elution of analytes with a solvent. This technique can quantitatively remove the analytes from solution and completely recover it in an appropriate solvent. In the process, SPE extracts the analytes from interfering compounds and concentrates the analytes in a small volume of solvent. The mechanisms of retention include reversed phase, normal phase, and ion-exchange.

The advantages of SPE compared to liquid-liquid extraction are faster process, lower solvent consumption, enormous cost saving, and the potential of automation. Additionally, SPE provides clean extracts and high recoveries.

Related Topicss:

1. General SPE Procedures

2. SPE Applications

3. FritlessTM Advantages

Further Questions? info@biomicsinc.com


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  Product Selection Guide:
SPE Format Options
Common SPE Sorbents
BauloTM Fritted SPE Columns
Fritless™ SPE cartridges

96 Wells FritlessTM SPE

SPE Accessories
  Technique Support:
Basic Theory of SPE
Fritless Advantages
General SPE Procedures
SPE References
SPE Application Notes
  Other Sample Preparation Products:
Supported L-L Extraction
L-L Micro Extraction
Protein Precipitation